Mark James
professor and vice chair
Department(s):
Global and Community Health - BSPH
Tropical Medicine
Email:
mjames@tulane.edu
Research Interests:
Immunity and immunopathogenesis in parasitic infections; cytokine responses to malaria; use of syntheic malaria peptides for diagnosis and epidemiological surveillance
Professional Achievements:
1990, 1996, 1997, 1998, 2005 Excellence in Teaching Award, Tulane School of Public Health and Tropical Medicine
1999 Chancellor’s Teaching Scholar Award, Tulane School of Public Health and Tropical Medicine
October 10, 1995 (issue date) Patent no. 5,456,911: synthetic malarial antigens and uses thereof.
1999-present Chair, Personnel and Honors Committee, Tulane School of Public Health and Tropical Medicine
2000-2005 Vice-chair, Institutional Review Board, Tulane Health Sciences Center
2001-present Editorial Board, Public Health Reports, Association of Schools of Public Health
2006-present Chair, Biomedical Institutional Review Board, Tulane Health Sciences Center
Educational Background:
PhD, University of Illinois, Urbana-Champaign. 1979
MS, University of Illinois, Urbana-Champaign, 1975
BS, University of Wisconsin, 1972
Publications:
Selected recent publications
Praba-Egge AD, Montenegro S, Cogswell F, Hopper T, James MA. 2002. Cytokine responses during acute simian Plasmodium cynomolgi and Plasmodium knowlesi infections. American Journal of Tropical Medicine and Hygiene, 67: 586-596.
Praba-Egge AD, Montenegro S, Arevalo-Herrera M, Hopper T, Herrera S, James MA 2003. Human cytokine responses to meso-endemic malaria on the Pacific Coast of Colombia. Annals of Tropical Medicine and Parasitology, 97: 327-337.
Muehlenbein M, Alger J, Cogswell F, James MA, Krogstad D 2005. The reproductive endocrine response to Plasmodium vivax infection in Hondurans. American Journal of Tropical Medicine and Hygiene; 73: 178-187.
Koehler JW, Bolton M, Rollins A, Snook K, deHaro E, Henson E, Rogers L, Martin LN, Krogstad DJ, James MA, Rice J, Davison B, Veazey RS, Prabhu R, Amedee AM, Garry RF, Cogswell FB. Altered immune responses in rhesus macaques co-infected with SIV and Plasmodium cynomolgi: an animal model for coincident AIDS and relapsing malaria. PLoS One. 2009 Sep 23;4(9):e7139.
Buekens P, Almendares O, Carlier Y, Dumonteil E, Eberhard M, Gamboa-Leon R, James M, Padilla N, Wesson D, Xiong X: Mother-to-child transmission of Chagas’ disease in North America. Maternal and Child Health (submitted).
Solarte Y, Zamora F, Manzano R, Rocha L, Castillo Z, James MA, Herrera S, Arevalo-Herrera M: Effects of anticoagulants on Plasmodium vivax oocyst development in Anopheles albimanus mosquitoes. American Journal of Tropical Medicine and Hygiene (submitted).
Personal Statement:
Dr. James' laboratory carries out research on parasite immunity, most of which is dedicated to the study of immunity to the malarial parasite. His focus has been on the use of non-human primate vaccine models, development of synthetic peptide-based immunoassays, and the study of cytokine responses to acute Plasmodium infections. Collaborations are ongoing with Dr. Socrates Herrera in Cali, Colombia. Dr. James is also collaborating with Dr. Eric Dumonteil, Universidad Autonoma de Yucatan (Mexico) in testing therapeutic vaccines for Chagas’ disease in the non-human primate model. Pilot studies are planned for year 2007 at the Tulane National Primate Research Center. We have funding from the Gorgas Memorial Research Institute, with additional pilot funding pending from the Primate Center, to initiate such trials. Finally, Dr. James, together with Dr. Buekens and Dr. Dumonteil, are planning joint studies in the Yucatan, Mexico and in Honduras on the incidence of congenital Trypanosoma cruzi infections.
Contact Information:
Professor and Vice Chair
Department of Tropical Medicine
Tulane University School of Public Health and Tropical Medicine
1440 Canal Street, Suite 2210
New Orleans, LA 70112
Phone 504.988.2503
Fax 504.988.7313
Level of Instruction:
graduate
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