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Young Hong, PhD
Assistant Professor
Department of Tropical Medicine
Tulane University School of Public Health and Tropical Medicine
1440 Canal Street
New Orleans, LA 70112
Phone: (504) 988-6946
Fax: (504) 988-7313
young@tulane.edu
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Research Interests:
Molecular entomology; gene expression in mosquitoes; mosquito/parasite interactions
Lab Webpage: https://sites.google.com/site/mosquitolab/
Educational Background:
- Post-doctoral, University of Notre Dame, Indiana
- Post-doctoral, Purdue University, West Lafayette, Indiana
- PhD,Purdue University, West Lafayette, Indiana
- MS, Korea University, Seoul, Korea
- BS, Korea University, Seoul, Korea
Professional Achievements:
- Tulane Research in Promise 2006
- Postdoctoral Fellowship American Heart Association 1997 - 1999
- The president's prize Student Competition, Entomological Society of America December 1992
- David-Ross Scholarship Purdue University 1991 - 1993
Selected Publications:
Ryoo, M.I., Y.S. Hong, and C.K. Yoo. (1991). Relationship between temperature and development of Lariophagus distinguendus (Hymenoptera: Pteromalidae), an ectoparasitoid of Sitophilus oryzae (Coleoptera: Curculionidae). Journal of Economic Entomology. 84 (3): 825-829.
Hong, Y.S. and M.I. Ryoo. (1991). Effect of temperature on the functional and numerical responses of Lariophagus distinguendus (Hymenoptera: Pteromalidae) to various densities of the host, Sitophilus oryzae (Coleoptera: Curculionidae). Journal of Economic Entomology. 84 (3): 837-840.
Reuveni, M., Y.S. Hong, P.E. Dunn, and J.J. Neal. (1993). Leucine transport into brush border membrane vesicles from guts of Leptinotarsa decemlineata and Manduca sexta. Comparative Biochemistry & Physiology A-Comparative Physiology. 104: 267-272.
Hong, Y.S., M. Reuveni, and J.J. Neal. (1995). A sodium- and potassium-stimulated tyrosine transporter from Leptinotarsa decemlineata midguts. Journal of Insect Physiology. 41 (6): 527-533.
Neal, J.J., D. Wu, Y.S. Hong, and M. Reuveni. (1996) High affinity transport of histidine and methionine across Leptinotarsa decemlineata midgut brush border membrane. Journal of Insect Physiology. 42 (4): 329-335.
Hong, Y.S. and Neal, J.J. (1997) Tyrosine transporter in larval Leptinotarsa decemlineata midgut brush border membrane. Insect Biochemistry & Molecular Biology. 27 (3): 193-200.
Li, C., C. Geng, H.-T. Leung, Y.S. Hong, L.L.R. Strong, S. Schneuwly, and W.L. Pak. (1999). INAF, a novel protein required for TRP Ca2+ channel function. PNAS, USA. 96 (23): 13474-9.
Yoon, J., H. Cohen-BenAmi, Y.S. Hong, S. Park, L.L.R. Strong, J. Bowman, K. Baek, B. Minke, and W.L. Pak. (2000). Novel mechanism of massive photoreceptor degeneration caused by mutations in the trp gene of Drosophila. J. Neuroscience. 20(2): 649-59.
Hong, Y. S., Yoon, Y., Geng, C., Bowman, J. D., and Pak, W. L. (2002). A single amino acid change in the fifth transmembrane segment of the TRP Ca2+ channel causes massive degeneration of photoreceptors. J. Biol. Chem. 277: 33884-33889.
Thomasova, D., Ton, L.Q., Copley, R., Zdobnov, E., Wang, X., Hong, Y.S., Sim, C., Bork, P., Kafatos, F.C., and Collins, F.H. (2002). Comparative genomic analysis in the region of a major Plasmodium-refractoriness locus of Anopheles gambiae. PNAS, USA. 99: 8179-84.
Holt, R.A., et. al. (2002). The genome sequence of the malaria mosquito Anopheles gambiae. Science 298: 129.
Hong, Y.S., Hogan, J.R., Wang, X., Sarkar, A., Sim, C., Loftus, B.J., Ren, C., Huff, E.R., Carlile, J.L., Black, K., Zhang, H.-B., Gardner, M.J., and Collins, F.H. (2003). Construction and Characterization of a BAC Library and Generation of BAC End Sequence-tagged Connectors for Genome Sequencing of African Malaria Mosquito Anopheles gambiae. Molecular Genetics and Genomics 268: 720-728.
Sarkar, A., Sim, C, Hong, Y.S., Fraser, M., Robertson, H., and Collins, F.H. (2003). piggyBac element related sequences are present in diverse eukaryotic genomes. Molecular Genetics and Genomics 270: 173-180.
Y. S. Hong, L. Q. Ton, and F. H. Collins. (2003). On Methods of Germ-line Transformation and RNA Interference in African Malaria Mosquito, Anopheles gambiae. J. Asia-Pacific Entomol. 6(2): 111-117.
Ali N. Dana*, Young S. Hong*, Marcia Kern, Maureen E. Hillenmeyer, Brent Harker, Neil F. Lobo, James R. Hogan, Patricia Romans, Frank H. Collins. (2005). Microarray study of hematophagy-associated expression of abdomen-derived genes in adult female Anopheles gambiae mosquitoes. BMC Genomics. 6:5.*: Equal contribution.
Sim C, Hong YS, Vanlandingham DL, Harker BW, Christophides GK, Kafatos FC, Higgs S, Collins FH. (2005). Modulation of Anopheles gambiae gene expression in response to o'nyong-nyong virus infection. Insect Mol Biol. 14:475-81.
Kang S, Hong YS. RNA interference in infectious tropical diseases. Korean J Parasitol. 2008 Mar;46(1):1-15.
Kang S, Sim C, Byrd BD, Collins FH, Hong YS. Ex vivo promoter analysis of antiviral heat shock cognate 70B gene in Anopheles gambiae. Virol J. 2008 Nov 5;5:136.
Choi CW, Hong YS, Kim SI. (2008). Application of free-flow electrophoresis/2-dimentional gel electrophoresis for fractionation and characterization of native proteome of Pseudomonas putida KT2440. J Microbiol. 46:448-55.
Yong Hun Jo*, Yong Seok Lee*, Se Won Kang, Weon-Gyu Kho, Hong Seog Park, Sang Haeng Choi, Yu Jung Kim, Young S. Hong, Mi Young Noh, Seung Han Oh, Iksoo Kim and Yeon Soo Han. (2011). Bioinformatic analysis and annotation of expressed sequence tags (ESTs) generated from Anopheles sinensis mosquitoes challenged with apoptosis-inducing chemical, actinomycin-D. Entomological Research 41 (2011) 53–59.
Young S. Hong, Seokyoung Kang, Manjong Han, Geoffrey N. Gobert, Malcolm K. Jones. (2011). High quality RNA isolation from Aedes aegypti midguts using laser microdissection microscopy. BMC Parasites and Vectors. 2011 May 19; 4:83.
Level of Instruction:
graduate
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